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Haemonetics Corp (NYSE:HAE)
Q2 2022 Earnings Call
Nov 9, 2021, 8:00 a.m. ET
Contents:
- Prepared Remarks
- Questions and Answers
- Call Participants
Prepared Remarks:
Operator
Good morning, ladies and gentlemen. Thank you for standing by and welcome to the Second Quarter 2022 Haemonetics Corporation Earnings Conference Call. [Operator Instructions] Please be advised that today's conference may be recorded. [Operator Instructions]
I would now like to hand the conference over to your speaker host today, Olga Guyette, Director of Investor Relations. Please go ahead.
Olga Guyette -- Director, Investor Relations
Thank you. Good morning, everyone. Thank you for joining us for Haemonetics second quarter fiscal '22 conference call and webcast. I'm joined today by Chris Simon, our CEO; and Bill Burke, our CFO.
This morning, we posted our second quarter fiscal '22 results to our Investor Relations website, along with our updated fiscal '22 guidance and analytical tables with the information that we'll refer to on this call. Additionally, we provided a complete P&L, balance sheet, summary statement of cash flows as well as reconciliations of our GAAP to non-GAAP financial results and guidance.
Before we get started, unless otherwise noted, all revenue growth rates discussed today are on an organic basis and exclude the impact of currency fluctuation, strategic exits of product lines, acquisitions and divestitures and the impact of the 53rd week in fiscal '21.
As in the past, we'll refer to non-GAAP financial measures throughout this call to help investors understand Haemonetics' ongoing business performance. Please note that these measures exclude certain charges and income items. Please refer to this morning's earnings release for details on excluded items, including comparisons with the same periods of fiscal '21 and a reconciliation to GAAP results.
Our remarks today include forward-looking statements and our actual results may differ materially from the anticipated results. Haemonetics cautions that these forward-looking statements are subject to risks and uncertainties, including the potential impact from the pandemic in our results and other factors referenced in the Safe Harbor statements in our earnings release and in our filings with the SEC. We do not undertake any obligation to update these forward-looking statements.
And now, I'd like to turn it over to Chris.
Christopher Simon -- President and Chief Executive Officer
Thank you, Olga. Good morning, everyone and welcome.
Before we discuss our second quarter results, I'd like to begin with the news we announced this morning that Bill Burke has decided to retire from Haemonetics effective next summer. Bill joined the company in August 2016 and has been a valuable advisor and partner to me while building Haemonetics' world-class finance team. Together, we have directed strategic financial initiatives, enabling us to best leverage our resources for investments in the people, products and processes that drove our turnaround and are fueling our long-term growth.
I'm grateful that Bill will continue to serve as CFO through the remainder of this year as we conduct a search for his successor. He has also agreed to work closely with his successor and the finance team to effect a seamless transition. I offer Bill my sincere appreciation for his many contributions to our company.
Now, on to the second quarter results. Today, we reported organic revenue growth of 5% for our second quarter of fiscal '22, an adjusted earnings per share of $0.60, down $0.02 or 3% compared with the second quarter of the prior year. Our performance in the quarter reflects revenue growth across all of our business units. And we are encouraged by our overall positive first half fiscal '22 results and the momentum we have built moving forward.
We are enthusiastic about our success so far. Our teams are demonstrating strength and resiliency and we anticipate robust growth through the second half of our fiscal year. We are advancing our market leadership by driving significant value for donors, collectors, patients and physicians around the world. We see clear evidence of upturn in our key markets, including meaningful increases in plasma collections, growth in demand for our hospital products and the performance of our blood center apheresis business.
However, based on the initial lag in recovery of our US sourced plasma collections, we have reassessed our expectations and now forecast total company organic revenue growth of 7% to 10%. In addition, due to uncertainties about inflationary pressures in our global supply chain, we have updated our fiscal '22 adjusted earnings per diluted share guidance to $2.40 to $2.65.
Let's discuss the business units. Plasma revenue increased 7% both in the second quarter and year-to-date. We saw important signs of recovery on a sequential basis, but the COVID-19 pandemic and associated government subsidies continue to have a dampening effect on the US sourced donor plasma pool.
North American disposable revenue increased 10% in the second quarter, driven by a 20% improvement in US collection volumes compared to the prior year as we observed meaningful recovery from the pandemic. Similarly, US collection volumes grew 14% sequentially in the second quarter, significantly outpacing the historic industry average seasonal improvement of 8%.
This represented our first quarter of sequential collection volume growth since the most recent US government stimulus programs were implemented in late calendar 2020 and early 2021. The improvement in collection volumes was partially offset by price adjustments, including the expiration of fixed-term pricing on historical PCS2 technology. These price adjustments will annualize during the fourth quarter of fiscal '22.
Collection center conversions remain on track. We will complete the upgrade of our customers to the latest version of NexLynk DMS software later this year and transition our major customers to NexSys PCS devices by mid-fiscal '23. Our NexSys platform with its YES and Persona protocols is a powerful tool to help our plasma customers, increase yield for collection, ensure continued safety, quality and compliance, enhance collection center productivity and provide solutions to help retain donors. We continue to receive positive feedback from NexSys customers who value the connectivity, increased speed, compliance and donor satisfaction.
Early adopters of our Persona technology are benefiting from an additional 9% to 12% plasma yield per donation. We anticipate additional Persona conversions over the second half of fiscal '22 as our customers strive to further increase US collection volumes to replenish depleted inventories. The improvement in US collections during the second quarter, despite the continued impact of the pandemic and associated government subsidies, provides evidence of recovery and momentum as we head into the second half of the year.
We expect continued improvement in US collection volumes during the third quarter, driven by the expiration of remaining economic stimulus programs, the normalization of income and savings rates and increased spending generally associated with the holiday season. This is consistent with the trends we observed in the third quarter of fiscal '21.
We continue to expect US collection volumes will return to pre-pandemic levels and grow from there. However, there is uncertainty around the timing and pace of the rate of collection volume recovery in the second half of the year. Even small shifts in this timing could have a meaningful impact on our fiscal '22 plasma organic revenue growth. Therefore, while we continue to assume significant and accelerated US collection volume recovery in the second half of fiscal '22, we are lowering our plasma organic revenue growth guidance to 10% to 20%.
The high end of our revised revenue guidance aligns with the midpoint of our previous guidance range of 15% to 25% and assumes a significant increase in collection volume, considerably higher than the 20% growth rate we observed in the second quarter. This trajectory assumes US collection volumes will return to pre-pandemic levels by late Q3 and continue into Q4.
The low end of our revised guidance range also assumes that second half US collection volumes will still grow considerably. But the rate of increase will be more consistent with the 20% growth we observed in the second quarter. At this lower trajectory, US collection volumes will not fully recover to pre-pandemic levels before the end of fiscal '22.
As collection volumes recover and fractionators replenish their depleted plasma inventories, we are well-positioned in a resilient end market. At a macro level, we continue to view the impact of the pandemic as temporary. The underlying demand for plasma-derived medicines is strong and our customers continue to expand their collection and fractionation capabilities and invest in R&D. As the industry recovers from the pandemic, we expect US-sourced plasma collections to return to 8% to 10% long-term growth. And we see potential to grow in excess of that as customers strive to replenish depleted inventories. We are fully ready to support this growth.
Moving to hospital. Revenue increased 10% in the second quarter and 18% year-to-date, primarily due to continued improvements in hospital procedures driving increased utilization of disposables, strong capital sales in North America and new business opportunities in Europe.
During the first half of the second quarter, we saw procedure volumes normalize across most geographies, with some headwinds in the second half of the quarter from the onset of the Delta variant, particularly in North America. As the number of COVID-related hospitalizations subsided, we saw additional recovery starting in mid-September.
Hemostasis Management revenue grew 21% in the second quarter and 26% year-to-date, driven by growth in the utilization of our products and strong capital sales as we continued to penetrate underserved cell elastic testing markets. North America, our largest market, led the charge in the adoption of our TEG 6s devices and increased utilization of cartridges benefiting from a second consecutive quarter of record capital sales. We also continue to benefit from increased market share in Europe with strong sales from both TEG 6s and ClotPro.
Cell salvage revenue declined 5% in the quarter as the Delta variant negatively impacted procedure volumes in the US and Japan for part of the second quarter. Disposables and capital both contributed equally to the decline, with capital being partially due to customer order timing following two consecutive quarters of strong growth. Cell salvage revenue grew 9% year-to-date, driven by recovery in procedure volumes and strong capital sales as we continue to update our latest technology.
Transfusion management revenue grew 5% in the quarter, primarily due to strong BloodTrack growth in the UK and 8% year-to-date driven by strong first quarter growth in both BloodTrack and SafeTrace Tx as we completed a series of new account installations in the US.
We reaffirm our guidance for 15% to 20% organic revenue growth in hospital, including mid-20s Hemostasis Management organic revenue growth. This growth rate is consistent with the recovery trajectory of hospital procedures we observed prior to the onset of the Delta variant and assume that procedures across all geographies will be fully recovered by the end of fiscal '22.
Our recently acquired vascular closure business delivered $21 million of revenue in the second quarter and $43 million year-to-date, doubling its revenue compared to the equivalent six-month period last year. Both VASCADE products delivered meaningful results through accelerated penetration of the new accounts and increased utilization within existing accounts. Early in the quarter, we experienced a seasonal dip in elective procedures, coupled with the impact of the Delta variant on electrophysiology and interventional cardiology procedures. As the impact of COVID-19 began to subside, we saw noticeable improvement in procedure volumes that we expect will continue through the second half of the year.
This growth will be further aided by VASCADE MVP earning the first ever FDA indication for same-day discharge for atrial fibrillation ablation. Procedure volume recovery, higher diagnosis rates, increased hospital efficiency and an overall move to standard of care facilitated by the same-day discharge indication give us greater confidence in the trajectory of VASCADE and we are increasing our fiscal '22 guidance range to $80 million to $90 million.
Our hospital business is becoming an increasingly significant driver of our success. Through the strength of our diverse portfolio and our innovation agenda, we are improving patient outcomes and hospital economics. Haemonetics' focus on improving the standard of care has never been more critical.
Blood center revenue increased 2% in the quarter and declined 2% year-to-date. Apheresis revenue grew 7% in the quarter and 2% year-to-date. Growth in apheresis in both periods was driven by a full recovery of platelet collections in Japan, partially offset by a reduction in plasma collections due to a prolonged COVID-related state of emergency. Additionally, our second quarter apheresis growth benefited from winning several new tenders in EMEA, which resulted in a series of initial capital device and disposal sales.
Whole blood revenue declined 11% in the quarter and 12% year-to-date, driven by lower-than-usual procedure volumes due to COVID-19 and previously discontinued customer contracts in North America. The recovery of platelet collections in Japan, coupled with the addition of the new tenders in EMEA, demonstrate the continued resiliency of our blood center apheresis business. Given this outperformance in the first half, we are increasing our fiscal '22 organic revenue guidance for the blood center business to a decline of 3% to 5%.
I'll now turn the call over to Bill.
William P. Burke -- Executive Vice President and Chief Financial Officer
Thank you, Chris. And good morning, everyone. Chris has already discussed revenue, so I will begin with adjusted gross margin, which was 52.6% in the second quarter, an increase of 40 basis points compared with the second quarter of the prior year. Adjusted gross margin year-to-date was 53.6%, an increase of 380 basis points compared with the first half of the prior year.
Our adjusted gross margin benefited from the addition of our VASCADE vascular closure business, continued growth savings from our operational excellence program and favorable mix from the remaining product portfolio as our business continues to recover from the effects of the pandemic. These benefits were partially offset by inflationary pressures in our global supply chain, including freight costs, previous divestitures and price adjustments.
Additionally, the sequential decline in adjusted gross margin of 210 basis points in the second quarter was primarily driven by inflationary pressures in our global supply chain, including freight costs. Adjusted operating expenses in the second quarter were $82.4 million, an increase of $16 million or 24% when compared with the prior year. As a percentage of revenue, adjusted operating expenses increased by 260 basis points and we're at 34.3%. Adjusted operating expenses in the first half were $169.5 million, an increase of $39.3 million or about 30% compared with the first half of the prior year.
The acquisition of our VASCADE vascular closure business has the largest impact on the increase in adjusted operating expenses. Also affecting the increase were increases in freight costs and higher research and development expenses as we broaden our project portfolio to strengthen our technology.
Our second quarter adjusted operating income was $43.8 million, an increase of about $1 million or 2%. In the first half, adjusted operating income was $81.7 million, an increase of $10.2 million or 14% compared with the same period in fiscal '21. The increase in adjusted operating income in both periods was driven by the improvement in adjusted gross margin partially offset by higher adjusted operating expenses.
Our adjusted operating margin was 18.3% in the second quarter and 17.4% in the first half, representing decreases of 220 basis points and 20 basis points respectively compared with the same periods in fiscal '21. Although our business continues to recover from the pandemic and we continue to generate additional savings through the Operational Excellence Program, we expect the inflationary pressures we have experienced in our global supply chain to continue at least through the remainder of fiscal '22. Accordingly, we are revising our adjusted operating margin guidance downward for fiscal '22 by 100 basis points to be in the range of 18% to 19%.
Our adjusted income tax rate in fiscal '22 was 22% in the second quarter and 23% in the first half compared with 19% and 13% in the same periods of fiscal '21. The adjusted income tax rate in both the first quarter and second half of fiscal '21 was abnormally low due to the benefit of higher share vestings and option exercises. We still expect our fiscal '22 adjusted tax rate to be 22%.
Second quarter adjusted net income was $30.7 million, down about $1 million or 3% and adjusted earnings per diluted share was $0.60, down 3% when compared with the second quarter of fiscal '21. In the first half, adjusted net income was $56.1 million, up about $1 million or 1% and adjusted earnings per diluted share was $1.09, up 1% when compared with the first half of fiscal '21. The adjusted income tax rate in the first half of fiscal '22 had a $0.15 downward impact on adjusted earnings per diluted share when compared with the prior year.
Our VASCADE vascular closure business is exceeding our original expectations and we expect this business to be accretive to adjusted earnings per diluted share in fiscal '22, an improvement over our original expectation of $0.15 to $0.20 dilution in the first year following the acquisition. We expect this overperformance will be driven by stronger commercial execution and improved capital structure when compared with the original deal model and will allow us to generate additional resources to fund growth investments across the company.
As we announced last quarter, we extended our Operational Excellence Program. This plan was launched two years ago to amplify efficiency, improve product and service quality and transform the way we make and deliver products. We continue to successfully achieve ongoing savings across this program, demonstrating the organization's commitment and resiliency. We continue to expect total gross savings of $115 million to $125 million from the Operational Excellence Program and we continue to anticipate approximately $33 million of gross savings in fiscal '22. Additionally, we continue to expect to incur $95 million to $105 million in restructuring and restructuring-related costs over the course of this program.
In the calculation of net savings in our Operational Excellence Program, we have included investments and inflationary pressures. With the escalation of abnormally high inflationary pressures in our global supply chain, we now expect no operating income benefit this year. We will update the total program's net savings when we provide guidance in fiscal '23. The delay in the anticipated timing of recovery of plasma collection volumes, combined with the inflationary pressures in our global supply chain, are significant enough to revise our fiscal '22 adjusted earnings per diluted share guidance to a range of $2.40 to $2.65 compared to our previous guidance range of $2.60 to $3.
Cash on hand at the end of the second quarter was $192 million, essentially flat since the beginning of the fiscal year. Free cash flow before restructuring and restructuring-related costs was $31 million compared with $38 million in the first half of the prior year. The lower free cash flow before restructuring and restructuring-related costs in fiscal '22 was due to higher accounts receivable as our revenue continues to recover from the pandemic and higher capital expenses, primarily related to the Operational Excellence Program, partially offset by lower inventory growth.
We have revised our fiscal '22 guidance of free cash flow before restructuring and restructuring-related costs to a range of $115 million to $135 million compared with our prior guidance range of $135 million to $155 million. The lower guidance to free cash flow before restructuring and restructuring-related costs is entirely due to the lowering of our adjusted earnings per diluted share guidance.
Before we open the call up to Q&A, I want to reiterate the key points that we hope you take away from today's call. Our second quarter and first half results showed continued recovery across our businesses. This improvement demonstrates the strength of the underlying demand for our products and services. We continue to see an encouraging recovery in plasma collection volumes, although the pace of recovery is different than our original projections with lingering effects from the pandemic. Plasma collection volume recovery was and continues to be the largest variable included within our guidance. We remain optimistic that a full recovery is underway and we believe there are no structural changes in the underlying market.
Our hospital business continues to grow double-digits, led by more than 20% growth in Hemostasis despite challenges from the resurgence of COVID-19 in the quarter. Vascular closure continues to excel on the strength of our market position and the opportunity created by higher diagnosis rates, increased hospital efficiency and an overall move to standard of care. The business is exceeding our expectations with strong revenue growth and increased leverage and is accretive to adjusted earnings per diluted share. The implementation of our Operational Excellence program is continuing to reduce our cost base and is critical to help mitigate the impact of inflationary pressures in our global supply chain particularly freight.
Lastly, our teams continue to work diligently on updating our long-range plan and we are looking forward to sharing it at our virtual Investor Day early next year.
Thank you. And now, I'd like to turn the call back to the operator for Q&A.
Questions and Answers:
Operator
Thank you. [Operator Instructions] And our first question coming from the line of Anthony Petrone with Jefferies. Your line is open.
Anthony Petrone -- Jefferies -- Analyst
Thank you. And good morning, everyone. And good luck, Bill, as you transition into retirement. Maybe to kick off with a few questions on plasma and guidance. Maybe Chris and/or Bill, kind of walk us through how the quarter progressed and particularly it looked as if earlier in the quarter there were signs of a more sort of protracted plasma reversal improvements earlier in the quarter which kind of gave way to some pressures toward the end of the quarter.
So maybe just a little bit on where the specific pressures were as the quarter evolved? Was it border centers? Was it just Delta constraint specifically? We've been hearing a lot about hospital staffing shortages. Was that at play at the plasma centers in the United States? So maybe just a little bit on the ebbs and flows of the quarter. And I have a couple of follow-ups.
Christopher Simon -- President and Chief Executive Officer
Yeah. Hey, Anthony. It's Chris. Thanks for the question. With regards to the progression, we are in the midst of recovery. We remain optimistic about the overall recovery. I think there's ongoing questions as there will continue to be around pace and timing and candidly from our original forecast probably one to two months off of that in terms of gaining that trajectory.
But if I just take you back because we have put a bunch of numbers out, so let me try to clarify where we are. We reported 14% growth in the first quarter. When we did our earnings call in August, we said that through the month of July, we had actually -- we're closer to 20% growth. And then, I spoke at Morgan Stanley Conference in September and said, we're actually inching up toward the mid-20s over the course of the remainder of the quarter, we came in as you saw from the results today at 20%, which as you head into third quarter, third quarter last year, we experienced meaningful growth. And we are forecasting that we all experienced meaningful growth again this third quarter.
Historically, the business ticks up on average across the industry 3% to 5%. We did well in excess of that last year. We expect to do well in excess of that again this year. The revised guidance range of 10% to 20% on the low end, as we said in our prepared remarks, contemplates continued 20% growth, very consistent with where we were in the second quarter. The high end of the range would be nearly double that at 35%.
And where we are today? And I think lesson learned about the jumpiness in this data, we're well within that range. And we feel confident in our revised guidance as best as we can, given, as you said, we don't control the southern border or we don't control the Delta variant. We are working hand-in-hand with our customers to make sure the centers are fully operational, that they are safe and perceived to be. And I think, the industry collectively is doing yeoman's work to drive this recovery. If we see the higher end of our range, we'll be back to pre-pandemic levels by our fiscal year-end.
On the low end of the range, that will carry on into FY '23. But the recovery is underway. We're confident there's nothing different structurally or longer-term. And in fact, as I said in the prepared remarks, as we get out ahead of this, the opportunity to grow in excess of the 8% to 10% historical average is in front of us and we're ready to support that given the need to replenish depleted inventories.
Anthony Petrone -- Jefferies -- Analyst
Just a couple of follow-ups there on the outlook, A, and then just safety stock levels industrywide. On the outlook now plus 10% to 20% revised for plasma, one of the larger fractionators recently came out and guided plus 15% to 25%, which was in line with the prior guide. So maybe just a little bit of reconciliation there.
And then, secondly, when you look at sort of safety stock levels, I know it's hard to sort of look beyond reported financials. But anything you can glean as to where kind of industrywide safety stock level sit heading into the back end of this year. And of course, if they are running low, that would sort of point to a need to overcollect, as you mentioned. I'll get back in queue. Thanks.
Christopher Simon -- President and Chief Executive Officer
Yeah. Thanks, Anthony. So, as you know, I won't comment on individual customers.The numbers can move around a bit. Folks report that they have different fiscal periods than we do which are still, as you know, through March 31. If someone's looking at a calendar year or a mid-year, it's going to be different. And we recognize and respect that.
I think our collectors do have other sources of plasma. Some of them are picking up third-party plasma, etc. So, there can be reasons why the individual forecasts are going to differ. From our vantage point, as we said, recovery is underway and we feel good about it. The lag candidly was more in the summer months and maybe a one to two-month delay in the trajectory that the industry is now achieving. And so, from our vantage point, we just have to call it based on what we saw this past summer and where we see it going forward. 10% to 20% is still robust growth. And we feel confident that collectively we can deliver on that.
In terms of the inventory levels that our customers maintain on frozen plasma, it's less than transparent and it's complicated. They've done a bunch of things to expedite the release of that inventory. It certainly had to manage end market demand for different indications and different formulations. We don't have a lot of visibility into that. We track it closely. And it's one of the reasons that we're bullish that as the recovery accelerates that they'll continue to accelerate certainly beyond anything getting us back to prior levels because there is a need as we did probably in the three years in the run up to the pandemic to help the industry build volume that build plasma volume storage. So, we're there. We're looking forward to support it. And it's just a question of the exact timing and pace from where we sit.
Anthony Petrone -- Jefferies -- Analyst
Thank you.
Operator
And our next question coming from the line of Andrew Cooper with Raymond James. Your line is open.
Andrew Cooper -- Raymond James -- Analyst
Hi, everybody. Thanks for the questions. Maybe just to follow-up with one more on the plasma trajectory. I know you sort of alluded to it, but can you give us a little bit more specific flavor for what you've seen through October and sort of where the big growth sits today if it's still consistent with that 20-ish-percent or has it picked up a little bit as we move beyond sort of the worst of the worst of the pandemic?
Christopher Simon -- President and Chief Executive Officer
Yeah. Thanks for the...
Andrew Cooper -- Raymond James -- Analyst
Of Delta, I should say.
Christopher Simon -- President and Chief Executive Officer
Yeah. Thanks for the question. As it pertains to the Delta variant and what we're seeing on the ground in centers, in part enabled by some of our digital applications, the centers are safe and fully operational. And it's been quite impressive to watch what our customers have been able to do to make it a good and rewarding donor experience. So, in that regard, we feel quite confident that collectively as an industry we can manage through the pandemic as it migrates and becomes an endemic going forward presumably.
In terms of where we are, obviously the data jumps around a bunch. We know we see a historical 3% to 5% increase in the third quarter. That's a combination of everybody being back at school, gearing up for the holiday spend and some other seasonal effects. Last year, we grew well in excess of that. We anticipate -- and the 10% to 20% guide fully anticipates that we're going to grow well in excess of that. We're a month into the quarter. I don't want to get in the habit of kind of drilling down on the weeklies because they're just too noisy. But we feel quite confident with the guide that we've given that what we're seeing quarter-to-date, we're well within the range and therefore kind of OK with what we're putting forth.
Andrew Cooper -- Raymond James -- Analyst
Okay. Great. Appreciate that. And then, maybe just on sort of some of the inflationary items, can you give us a little bit more flavor for maybe what's great? Like there shouldn't be a ton of laser, but that's something we've heard a lot of folks talk about. So how do we think about those two versus some of the other inputs? And then, whether in fiscal '22 or longer-term, any ability to start passing through some of those inflationary items to the customers or how else can you offset some of those items?
Christopher Simon -- President and Chief Executive Officer
Bill, you want to take a run at that?
William P. Burke -- Executive Vice President and Chief Financial Officer
Sure. Hi, Andrew. On the inflationary pressures, most of the pressures that we're seeing are freight-related, specifically later in the second quarter. I think everybody has seen the news, right? We started to really see those freight costs go up. But in addition, we are seeing slightly higher raw material costs too and that goes back even into our first quarter. We don't -- in our guidance, we haven't anticipated that any of those costs will bounce back, right? We just are expecting pretty much a steady state right through the end of this fiscal year.
And then, on the second part of your question regarding the pass through of costs to customers, I think it's just a wait-and-see right now. We have our eye on it and it's something where we're looking at, but I think we're just going to have to wait longer-term to see what happens in regards to the cost coming back to normal.
Christopher Simon -- President and Chief Executive Officer
Yeah, if I can just build on that.
Andrew Cooper -- Raymond James -- Analyst
[Speech Overlap] Thanks, everybody. Oops, sorry, guys.
Christopher Simon -- President and Chief Executive Officer
If I can build on that, Bill, what I would say is, one of the things that we are proud of and I think we've had a lot of recognition from our customers is business continuity and our own employees' safety and health, which is a requirement for that. So we've worked very hard to keep all of our manufacturing and distribution sites fully operational. There's been lots of challenges we've had to rejigger and the international freight piece has been highlighted. It's in particular a real headwind for us.
But the reality is, we have been able to maintain business continuity throughout. And I think, as we get into the winter and spring, we're having the right conversations with customers to make sure that we can ensure that our contracts are long-term contracts both on the hospital side and with our collectors. But we'll continue to explore what's fair and equitable in terms of what we're putting forth.
Andrew Cooper -- Raymond James -- Analyst
Great. Thanks, again.
Operator
And our next question coming from the line of Drew Ranieri with Morgan Stanley. Your line is open.
Drew Ranieri -- Morgan Stanley -- Analyst
Hi. Thanks for taking the question. Just start to go back to the guidance in plasma here. But just when we look at the low end and high end, Chris, I hear your remarks, which is we're still in kind of an uncertain environment. So, can you just give us a little bit more color on what you're seeing at the ground level at centers and really your confidence that you are able to achieve maybe at least the lower end of the guidance. Just maybe help us better appreciate how you're building up that lower end in terms of volume and pricing trends.
And then, you did call out the southern border issue. I know you've previously mentioned that maybe it was like 100 basis point on a headwind, but has that changed at all in terms of your thinking and guidance? Thank you.
Christopher Simon -- President and Chief Executive Officer
Yeah. Thanks for the question, Drew. So, as it plays out, volume and pricing do work together here, which we've talked about, the price challenges through the first part of the year. Some of those were associated with legacy PCS2 agreements, things that have expired. We also had the fact that we have volumetric pricing in some cases where the utilization was down, we had challenges there. So, the good news is, this works together.
What we've guided for assumes on the low end of the range that we build on the performance we've already achieved year-to-date, in particular 20% year-over-year growth in the second quarter and that we continue upon that trajectory. It gets harder for sure. The third quarter last year was a meaningful uptick, well beyond that 3% to 5% historical. The same factors apply this year. We saw the end of the majority of the federal stimulus programs back at the end of the summer, kind of August and into September. We've had a similar dynamic here this year. And we track closely savings rate and household income and the numbers correspond with what we observed last year at this time.
So, there can certainly be challenges associated with new variants. And we don't foresee additional stimulus. There are some lingering programs that could have an effect, but the majority of it tracks closely to what we observe previously and that gives us more confidence in this environment forecasting forward, where I think we see this also is the continued pressure on our customers. They've done their part. They've raised remuneration levels, they've opened new centers and they continue to invest longer-term in fractionation and R&D, which gives us confidence that, yeah, the second half is no small feat from where we sit. But we revised the guidance with the level of confidence that we'll deliver in that range.
Drew Ranieri -- Morgan Stanley -- Analyst
Got it. And then, just kind of the other topic seen in medtech was staffing shortages at hospitals. Can you give a little bit more detail on what you're seeing or what you saw in the quarter and how that's embedded in your guidance? I mean, the vascular closure business, I think, continues to be a bit above our expectations, but maybe how staffing shortages could relate to that business. Thank you.
Christopher Simon -- President and Chief Executive Officer
Yeah. Thanks, Drew. We compete in four distinct segments in the hospital space. And our transfusion management business is largely a software business. It's largely a subscription revenue unaffected by this, right. There's a little bit of movement in terms of how fast we can do installations. Our teams have been creative and resilient and figure out how to take a hospital live on our software with minimal time on site, so no effects there.
So, salvage was down a bit in the quarter due to the Delta variant, not due to staffing shortage but largely due to the Delta variant. As procedure volumes recovered, the performance recovered. And we feel good about that going forward. The two leading pillars of growth for us in hospital, TEG and VASCADE, are doing well and have not been affected by staffing shortages where we see that in other sectors for sure. I hear a lot about reconstructive orthopedics, for example. We're not in that space, right, in the main. So, what we're seeing in cardiology and cardiac surgery and trauma has been unaffected by staffing shortages. Delta variant matters. In some cases, it's a positive. In other cases, it's a headwind.
Electrophysiology is, we're getting to learn that space better, is just more traditional seasonality. And as I said in the prepared remarks, we had a bit of a lull in the summer as everybody, including the practicing clinicians, took some time off, well-deserved, and then things came roaring back in September. And we expect that momentum continues through the second half of the year, which is what gave us confidence to raise our guidance there.
Drew Ranieri -- Morgan Stanley -- Analyst
Thanks for taking the questions.
Operator
And our next question coming from the line of Mike Matson with Needham & Company. Your line is open.
Mike Matson -- Needham & Company -- Analyst
Yeah. Good morning. Thanks for taking my question. I guess, I'm still just struggling to really understand what's going on with pricing in the plasma business. I think you said the volumes were up. I turned the call a little late, but I think it was around 20% for the quarter. But your overall sales for the business organically was up about 7%, is that right? And 13% -- is that 13% all from pricing and what's driving that? When will that kind of go the other way around?
Christopher Simon -- President and Chief Executive Officer
Yeah, Mike. Appreciate the question. Your numbers are right. That's what we've put out. I think the first and the largest factor is pricing associated with legacy PCS2 agreements. So none of this is around the new technology NexSys or Persona. It's legacy PCS2s and specifically, as we've called out, we had a term-bound agreement with one of our large customers. That agreement has reached the end of that period and no longer continues. That will annualize in our fourth quarter of this year. There's also some effects on volume, as I mentioned just a moment ago, that works against us. As the volume recovers to the point that 20% on the low end of the range that we just talked about, we'll get the benefit of that kind of passing through.
There's some smaller effects as it pertains to mix for liquids, for example. We had a spot buy last year in the quarter that didn't repeat obviously and that's the challenge, and the pricing in Europe is different, and in Europe ebbs and flows as part of our mix, it will be -- would be a part of that, but that's -- they're the main factors. The good news is annualization and the return of volume, coupled with the benefit we are now receiving from the ongoing rollout of NexLynk and NexSys and now, as part of this, the continued rollout of Persona, all of which will be positive factors for us as the year progresses.
Mike Matson -- Needham & Company -- Analyst
Okay. So, it sounds like you had -- you have one large customer that you had a contract with some pricing locked in that expired, and then the new pricing you're getting from them is substantially lower. Am I understanding that right?
Christopher Simon -- President and Chief Executive Officer
We priced up to develop a piece of at the time which was proprietary technology. There was a five-year limit on it. This contract predates Bill and I, it was a long lived thing. It expired a year ago and we kind of worked through the comp of that expiry.
Mike Matson -- Needham & Company -- Analyst
And the pricing step down significantly after that fixed five-year period was up effectively.
Christopher Simon -- President and Chief Executive Officer
Okay.
Mike Matson -- Needham & Company -- Analyst
And so that will be a headwind through the end of '22, is that fiscal '22?
Christopher Simon -- President and Chief Executive Officer
Yeah.
Mike Matson -- Needham & Company -- Analyst
Okay. All right. And then, I guess, with regard to CSL, do you have any indication as to whether or not they wanted to extend the contract for another year and when do you -- when would they have to notify you of that?
Christopher Simon -- President and Chief Executive Officer
Yeah. What we've communicated on CSL, that agreement, which dates back to 2006, has one more unilateral extension period. So, if CSL chose to extend the contract beyond the 30th of June in 2022, they could extend that for one additional year. They would need to notify us six months in advance of that of their intention to do so. What we communicated last April was that they had come to us and said they were not going to extend beyond the current period. And there's been no change in that to-date.
Mike Matson -- Needham & Company -- Analyst
Okay. Got it. Then my final question, just on the freight costs. So, we've heard this from a lot of companies that's not surprising in that regard. But I was wondering, are your freight costs may be higher than sort of normal putting aside inflation because of the NexSys upgrades? I mean, are you having to ship around a lot of these NexSys units to plasma centers and things like that? Is that part of why it's hitting you harder maybe than some other companies?
Christopher Simon -- President and Chief Executive Officer
Yeah. I'll let Bill break it down for you. But our supply chain cost, right, we've avoided any disruption. But our factors -- the number one factor is international freight. And yes, a large number of our devices, both NexSys and TEG 6s, are produced overseas. And we need to get them to the US, which is our largest market in both cases, that's expensive. And we've taken steps to make sure we'll have the equipment here in the US when it's needed. So, that's part of the challenge there.
Another inflationary challenge we're grappling with is resin, right, in all of our plastic components. And particularly early in the year, early in the pandemic -- earlier in the pandemic, we saw some real price increases. We think we've managed through that, but we're working through that inventory as we speak. And that's why you're seeing it pass through our P&L the way it does.
Mike Matson -- Needham & Company -- Analyst
Okay. Got it.
Operator
[Operator Closing Remarks]
Duration: 48 minutes
Call participants:
Olga Guyette -- Director, Investor Relations
Christopher Simon -- President and Chief Executive Officer
William P. Burke -- Executive Vice President and Chief Financial Officer
Anthony Petrone -- Jefferies -- Analyst
Andrew Cooper -- Raymond James -- Analyst
Drew Ranieri -- Morgan Stanley -- Analyst
Mike Matson -- Needham & Company -- Analyst
This article represents the opinion of the writer, who may disagree with the “official” recommendation position of a Motley Fool premium advisory service. We’re motley! Questioning an investing thesis -- even one of our own -- helps us all think critically about investing and make decisions that help us become smarter, happier, and richer.
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